Partial lipodystrophy and dermatomyositis
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چکیده
منابع مشابه
Partial lipodystrophy and dermatomyositis.
In 1978, an 11-year-old boy began to notice proximal weakness in his limbs together with facial erythema; palpebral violaceous edema; and erythematous papules on his elbows, knees, and over the metacarpophalangeal joints. A diagnosis of polymyositis/dermatomyositis was made. He was treated with oral prednisone, which caused the symptoms to disappear promptly. In 1980, proximal weakness, dysphag...
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A patient with partial lipodystrophy, fatty liver and cirrhosis, and autoimmune thyroid disease is described. Treatment with thyroxine led to partial improvement in the hepatic abnormality.
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The association of coeliac disease and partial lipodystrophy is described. The patient also had deficiencies of serum IgA and C3 complement (the latter associated with partial lipodystrophy). In addition, there was subclinical dermatitis herpetiformis confirmed by skin biopsy. The facial wasting of fully developed partial lipodystrophy may be misinterpreted as a sign of malabsorption but the fa...
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A 31 year old female presented to the ante-natal clinic at 9 weeks of her pregnancy. She was diagnosed as having diabetes mellitus, 5 years previously and was on oral hypoglycemic agents. She also had hyperlipidemia on previous laboratoiy investigations. She conceived soon after her marriage. There was no family history of diabetes or other abnonnalities. When seen initially, she had almost com...
متن کاملPotential association of LMNA-associated generalized lipodystrophy with juvenile dermatomyositis
Background Juvenile dermatomyositis (JDM) is an auto-immune muscle disease which presents with skin manifestations and muscle weakness. At least 10% of the patients with JDM present with acquired lipodystrophy. Laminopathies are caused by mutations in the lamin genes and cover a wide spectrum of diseases including muscular dystrophies and lipodystrophy. The p.T10I LMNA variant is associated wit...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 1991
ISSN: 0003-987X
DOI: 10.1001/archderm.127.12.1846